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Reflexes were normal in the bilateral upper extremities but absent in the bilateral patella and ankles
But there were concerns about engagement (answers became automated by time, motivation fell over the course of the study), which may be related to the duration of the study
The activation of SREBP by mTORC1 also increases flux through the pentose phosphate pathway, leading to the production of NADPH and other intermediate metabolites necessary for cellular proliferation and growth
Wegovy works similarly to Ozempic by acting on GLP-1 receptors to regulate appetite
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