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Who should avoid Tirzepatide: Tirzepatide (Mounjaro, Zepbound) carries similar restrictions and is contraindicated in: Individuals with a personal or family history of MTC Those with MEN 2, due to the same cancer-related concerns People who have experienced severe gastrointestinal issues, such as chronic pancreatitis or gastroparesis Patients with a known hypersensitivity to tirzepatide or any of its components As always, anyone considering these medications should talk with their healthcare provider about their personal health history and risk factors
The three-way comparison between semaglutide, tirzepatide, and retatrutide continues to evolve as more clinical data becomes available
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Using a one-way ANOVA model ( = 0.05, six groups, n = 7 per group equivalent), the observed effect size (Cohens f) was 1.59, corresponding to an value of 0.72
