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Individuals with B12 Deficiency B12 deficiency symptoms include fatigue, weakness, numbness or tingling in the extremities, tongue soreness, depression, and even memory issues

In fact, 83.5% of the patients who developed complications at the end of the study already had DR at baseline, and the level was not described in the paper

If you push through and keep eating anyway, you might experience GI issues like abdominal pain, diarrhea and vomiting

It is possible that the latter group might find a reduction in the efficacy of their HRT when using tirzepatide (for the same pharmacokinetic reasons discussed regarding contraception), but the likelihood and magnitude of this is unknown