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This preclinical study shows that boosting GSH metabolism reduced oxidative stress, neuroinflammation, and plaque while improving memory in mice with Alzheimers

From there the voluntary muscle activity was recorded from the most caudal pair of electrodes, followed by measurement and recording of the average motor unit potential (UMP) and the compound motor action potential (CMAP)

Brunton LL, Knollmann BC, Hilal-Dandan R

Across dozens of studies, daily astaxanthin doses between 4mg and 12mg have been linked to improvements in skin hydration, elasticity, and UV resilience, as well as benefits for eye comfort, exercise recovery, and cognitive performance.1 2 3 5 6 Lower doses (46mg per day) often support skin and eye outcomes, but research suggests 12mg daily may unlock even broader effects.1 7 13 At 12mg, trials show improved endurance performance including faster cycling time trials and reduced muscle-soreness markers.3 8 Other studies point to enhanced cognitive function and sleep quality, benefits that tend to appear near the upper end of the dosing range.4 9 Taken together, these findings helped establish 12mg per day as the most compelling astaxanthin dose in the scientific literature