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35 Furthermore, the RCT LIGHT-ON (NCT02147925) compared the effect of liraglutide, sitagliptin and insulin glargine, when added to metformin in diabetic patients, exhibiting statistically significant results, in favor of liraglutide and sitagliptin, regarding body weight, visceral adipose tissue and liver fat content reduction
Only GLP-1RA reduced the risk of nonfatal stroke (RR = 0.84), as compared with placebo
affecting almost all methylation reactions in the body
The failure modes: Packaging inadequacy: Not enough gel packs or insulation for the shipping duration and exterior temperature
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