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These results suggest that NGF synthesis is modulated by changes in the redox cellular state, despite the differences in the time scales of these responses, probably due to the specific characteristics of the target organ, drug mechanisms of action and kinetic disparities

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All adverse event data in this article comes from two sources: the Phase 2 trial published in the New England Journal of Medicine (Jastreboff et al., 2023) and the TRIUMPH Phase 3 program data presented at medical conferences

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