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These mechanisms make it a key peptide in studies focused on dermal rejuvenation, neuroprotection, and systemic repair

For decades, GPX typically uses glutathione (GSH) as a reducing agent in catalyzing the reduction of H 2 O 2 or organic hydrogen peroxide to water or corresponding alcohols, respectively ( 2 O 2 and rapid reduction by GSH (Handy et al., 2021)

Metabolic abnormalities were HDL-c 26,3mg/dl, triglycerides 223mg/dl, insulin 58,3UI/mL, HbA1c 5,8%, and MASLD

Oxidative stress further amplifies proteolysis by increasing Beclin-1 and LC3-II expression and stimulating 20S proteasome activity, independent of ubiquitination