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This binding triggers the cascade of intracellular events that eventually lead to the activation of the PI3/AKT and MAPT pathways
In the study of glioblastoma, RSL3 inhibits the activity of GPX4, drives the occurrence of ferrozois and induces oxidative death of glioblastoma cells, providing new therapeutic ideas for glioblastoma (Xu et al., 2021)
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