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The muscle mass gain observed with strength training is mainly regulated by the activation of the mammalian target of rapamycin complex (mTOR), a key modulator of protein synthesis and ultimately of skeletal muscle hypertrophy (Reference Hoppeler35)

A doctor can help decide which option matches the underlying cause

Data were pooled using random-effects models with subgroup analyses by drug type and treatment duration (3, 6, and 12 months)

Better prediction means: More patients receiving treatments that work for them Fewer patients experiencing ineffective therapy or side effects More durable weight and metabolic outcomes More sustainable access to GLP-1 therapies Following these results, the collaboration is expanding to 25,000 patients to validate efficacy signals and identify predictors of safety and tolerability