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El proceso requiere vitamina C, vitamina B6, niacina y hierro como cofactores lo cual explica por qu las deficiencias nutricionales compuestas (comunes en dietas muy restrictivas o en personas mayores) reducen la produccin endgena

The novel DA-CH3 dual incretin restores endoplasmic reticulum stress and autophagy impairments to attenuate Alzheimer-like pathology and cognitive decrements in the APPSWE/PS1DeltaE9 mouse model

The peptide modulates transforming growth factor pathways involved in neuroinflammation resolution which aligns with the IL-6/TNF- reductions seen in the preprint

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