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Thus, unlike many other nucleoside-analog antineoplastic agents, the cytoxic effects of pentostatin do not appear to be attributable directly to the drug or its metabolites but instead appear to result indirectly from the effects of the substrates for adenosine deaminase (adenosine and deoxyadenosine) and/or their metabolites

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The current administrations potential easing of FDA restrictions could play a pivotal role in accelerating this trend. According to Mintel, 3.7 million people globally will be 100 years old or older by 2050, eight times as many as in 2015, which is one reason why consumers are making concerted efforts to improve health and live longer

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