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2016;138:e20154324
Xu R, Wang D, Wang C, Zhang G, Wei G (2018) Improved S-adenosylmethionine and glutathione biosynthesis by heterologous expression of an ATP6 gene in Candida utilis
Loss of glial homeostasis, BBB disruption, tanycyte remodelling and neuronal resistance to insulin and leptin lock the system into a state of maladaptive #neuroinflammation
The mechanism likely involves the same angiogenic pathway: bone repair is acutely dependent on vascularization of the fracture gap, and BPC-157's VEGF-stimulating activity addresses this bottleneck directly
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