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However, beta blockers can reduce plasma renin activity and be counterproductive in those with low blood volume
3739 While it is encouraging that the weight loss achieved with GLP-1/GIPGLP-1 receptor agonists approaches levels typically seen after bariatric procedures such as gastric bypass or sleeve gastrectomy, the rapid regain of a significant portion of the lost weight after treatment discontinuation, accompanied by a reduction in lean body mass, raises new clinical concerns
FDA-approved GLP-1s arent designed to be split into tiny doses, so people turn to compounded versions
Vollmer DL, West VA, Lephart ED
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