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Due to a lack of SCFAs, -synuclein can move from the stomach to the brain more readily, which heightened intestinal permeability and the pathological dissemination of the protein (41)

Acknowledgements This work was funded Funding of State Key Laboratory of Oral Diseases (SKLOD201527), the youth start-up fund (2015SCU11013) and the National Undergraduate Training Programs for Innovation and Entrepreneurship (201510610117)