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Decreased levels of TNF- and IL-6 indicate that NNMT inhibition not only modulates metabolism but also improves the inflammatory microenvironment, a key component in metabolic disease development and insulin resistance
National Diet and Nutrition Survey: Headline Results from Years 1, 2 and 3 (combined) of the Rolling Programme 2008/09 2010/11 (Report)
PMID 19237716
Full-length growth hormone produces fat loss but also elevates IGF-1 (with implications for cell proliferation and aging), worsens insulin sensitivity and elevates blood glucose (problematic for diabetics and pre-diabetics), promotes muscle growth and protein synthesis (which may be desired or unwanted depending on goals), causes fluid retention and edema in many users, and requires careful medical monitoring with regular blood work
