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at Seoul National University demonstrated that AHK-Cu stimulated the elongation of human hair follicles in ex vivo organ culture, increased dermal papilla cell proliferation at picomolar to nanomolar concentrations, and upregulated vascular endothelial growth factor (VEGF) expression the growth factor most critical for perifollicular blood supply
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This "paradoxical response" (where treatment temporarily makes symptoms worse) includes: Numbness and tingling Shooting pains Joint pain Increased sensitivity Temporary inflammation (swelling and irritation) While these symptoms generally indicate that treatment is working (as nerves begin to repair themselves), they can be distressing for patients and may require additional treatment for comfort
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