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IP3 may induce calcium ion release, while DAG may activate protein kinase C (PKC), potentially amplifying the signaling cascade and possibly stimulating the release of growth hormone from pituitary cells
The contact time during washing matters too
Rheumatology 57 , 656660 (2018)
To be fully transparent, one thing that shows up in independent ingredient reviews is the small amount of ethanol in the formula, which is flagged for caution on its own, though here it's used in a tiny quantity as a natural preservative and carrier, not as a primary ingredient
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