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This article examines what the science and UK clinical guidance actually say about B12 supplementation and weight loss, identifies who genuinely needs B12 supplementation, outlines safe dosage according to NHS and BNF recommendations, and sets out the evidence-based weight management strategies endorsed by NICE

Red blood cells help carry oxygen throughout the body and require vitamin B12 to function

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Hydroxocobalamin is the NHS-preferred B12 injection formulation, prescribed as a prescription-only medicine for confirmed deficiency states including pernicious anaemia and malabsorption disorders