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Algorithm-driven approvals without documented review introduce risk, particularly where complex comorbidities, safeguarding issues or nuanced mental health considerations are present 8,9
Most users experience improvement by weeks 48 as their body adapts, though some remain affected throughout treatment
They only stimulate insulin release when blood sugar is elevated
The late responder data also showed that while late responders achieved somewhat less total weight loss than early responders, the clinical significance was still substantial
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