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The role of ghrelin in regulating growth hormone secretion and energy metabolism. Endocrinology
Particularly insightful mechanistic evidence comes from a medaka fish NAFLD model, where metabolomic analysis revealed that L-carnitine not only reduced hepatic lipid deposition but also significantly elevated hepatic -oxidation end products (acetyl-CoA and ATP) while upregulating antioxidant enzyme superoxide dismutase 2 (SOD2) (35)
Significant upregulation was observed in cap-dependent translation in cells upon SIRT2 inhibition using AGK2 (Fig
Molecules 27 (5), 1620
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