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Inhibiting GSTP1 activity has the potential to amplify chemotherapys cytotoxic effects by reducing drug detoxification and increasing oxidative stress in tumor cells (Ozcan et al
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And if you mean guaranteed safe for every person, that is not the case either
Results of the Dapagliflozin and Prevention of Adverse Outcomes in Chronic Kidney Disease (DAPA-CKD) trial, which compared dapagliflozin (10 mg once daily) to placebo, found that dapagliflozin was associated with a 44% reduction in a composite of adverse kidney outcomes and a 29% reduction in death from cardiovascular causes or hospitalization for heart failure
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