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CDC summarizes USP guidance: date an opened multi-dose vial at first puncture and discard it within 28 days unless the manufacturer states another opened-vial date. The dose count and 28-day window together require three vials for the 12-week protocol
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burned a bit at first but got used to it
Manage underlying health conditions: Treating conditions like liver disease, kidney dysfunction, or blood disorders can help bring B12 levels back into a normal range 7 , 11
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