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Younk LM, Mikeladze M, Davis SN

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Because of the large amounts of haemoglobin compared with the amount of drug given this would be inconsequential, were it not for the fact that the oxidised active metabolite can be recycled back to the active metabolite by reduction with NADPH (reduced nicotinamide adenine dinucleotide phosphate) in the erythrocyte

While results can last with ongoing care, they are not permanent