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Panel B shows the relative stability of GSH during the cycle (varying from 5,500 to 7,900 M)
Therefore, the deletion of the GDH2 gene will certainly impact on the catabolism of arginine and proline, considering that Gdh2 is the main enzyme capable of converting glutamate into -ketoglutarate through the reduction of NAD +
Why the Glutathione Index Is the Best Indicator of Brain Oxidative Stress The GSH/GSSG ratio reflects the activity of the enzyme glutathione reductase which is responsible for the transformation of GSSG (used, oxidised) to GSH (the reduced or fully loaded form that acts as a radical scavenger)
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