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Diabetic retinopathy: Rapid improvement in blood glucose control has been associated with worsening of diabetic retinopathy in people with type 2 diabetes, as observed with semaglutide
The side effects of semaglutide, particularly the gastrointestinal ones, occur directly because of how the drug works
If its not, one should consult their doctor
For current practice, the most defensible use of GLP-1RAs is as a time-bounded metabolic optimization strategy in women with meaningful obesity/insulin-resistance burden, with reproductive endpoints interpreted as potential downstream gains rather than guaranteed direct effects (17, 111, 112, 124)
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