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Sensitivity analyses were performed to explore the sources of higher statistical heterogeneity and funnel plots were examined for the assessment of publication bias

Specifically, participants with hyperphagic depression showed a positive association between postprandial change in ghrelin levels and anticipatory food reward responses in the VTA and left hypothalamus, while participants with hypophagic depression showed a negative association in the right hypothalamus (Cerit et al., 2019)

Medically Important Alterations in Transport Function and Trafficking of ABCG2

This is why the decision to combine these medications requires careful, individualized clinical judgment rather than a blanket recommendation in either direction