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A Comment in @TheLancetEndo discusses the effects of GLP-1 receptor agonists on skeletal muscle mass: hubs.ly/Q02QBfSp0 GLP-1 receptor agonists, which are effective for weight loss, can cause substantial muscle loss
Most patients report that side effects at each new dose are milder than they expected, especially if they've successfully adapted to the previous level
Wadden Researchers analyzed data from the SURMOUNT-1, SURMOUNT-2 and SURMOUNT-3 trials
The changes in adenine nucleotides measured in glucose-stimulated rodent islets occur in beta cells but not in alpha cells and are also observed in human islets
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