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If either compound has lower-than-stated purity or content, the actual administered dose differs from the calculated dose, compromising research validity
This persistent state, referred to as anabolic-steroidinduced hypogonadism (ASIH), has been attributed to prolonged suppression of hypothalamic GnRH signalling, desensitisation of pituitary gonadotropes, and potential structural or functional impairment of Leydig cells (79)
While GLP-1 agonists are not prohibited, their use in weight-class sports raises ethical questions about artificially manipulating body weight for competitive advantage
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