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Multiple reviews and meta-analyses show that berberine supplementation can modestly improve fasting glucose, HbA1c, and other cardiometabolic markers across diverse adult populations.64 65 While its effects are not dramatic, theyre repeatable and biologically plausible, which is why berberine is often discussed alongside diet and lifestyle strategies for metabolic risk
Potential side effects could range from mild to severe, including allergic reactions, injection site complications, and systemic effects
Half-life How long it takes for half of the compound to leave the body
doi: 10.1016/j.bbadis.2018.05.012 127 BruenRCurleySKajaniSCreanDOReillyMELucittMBet al
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