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But a new medical study suggests these drugs, known as GLP-1 receptor agonists, may be doing something far more interesting behind the scenes: calming an overactive immune system, particularly in people with mast cell activation syndrome (MCAS)

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Switching from semaglutide to tirzepatide as a one-time transition does produce additional weight loss in many patients, but this appears to be due to tirzepatide being a more effective medication overall rather than the switching itself providing benefit