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Treatment with either lovastatin or lapaquistat appeared to reduce squalene levels even further, as they both target enzymes upstream of squalene synthesis, while conversely, NB-598 treatment produced at least a 100-fold increase in squalene levels in host cells (Fig 3D, right)
Presented for research literature review only Dennery PA (2001)
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These findings are expected to influence the defenselessness of alcohol abuse [31]
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