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That's not a minor difference
DNA methylation markers in obesity, metabolic syndrome, and weight loss
illustrated how the selective permeability of the blood-brain-barrier (BBB) and bloodCSF barrier, combined with the spatial distribution of glutathione-metabolizing enzymes, underlies region-specific vulnerability to oxidative injury in the CNS (9)
This effect is more common when glutathione is taken in very high doses for an extended period
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