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The most commonly reported side effects at therapeutic doses include mild nausea, particularly in the first week of a protocol, which typically resolves by day 7 to 10 without any dose adjustment

Optimization and Plateau Considerations (Weeks 12-16+): After 12-16 weeks of use, the rate of body composition change may slow as users approach their genetic set points or as the body adapts metabolically

A lighter, leaner body may reach similar exposure at fewer milligrams while showing a larger heart-rate response

You should discard Dupixent if its been: frozen exposed to temperatures over 77F (25C) left out of the fridge for 14 days or more Youll also need to discard Dupixent if the solution inside the pen or syringe is cloudy or discolored