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[4] [5] Patients considering these treatments should understand that they are not a substitute for lifestyle modification or evidence-based weight management strategies endorsed by NICE

But with their success (and cost) has come a flood of imitation from those looking to capitalize on their popularity

This effect is thought to be mediated through GLP-1 receptors in the cardiovascular system and is generally not clinically significant, though patients with certain arrhythmias or those sensitive to heart rate changes should be monitored

The product is rigorously assessed in a certified laboratory and free from any additives and preservatives