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Similarly, PDE3 inhibitors such as milrinone and cilostazol demonstrate cardiovascular adverse effects, including arrhythmias, tachycardia, and palpitations, attributable to PDE3 expression in myocardium and vascular smooth muscle (Kuzmiszyn et al., 2022)

A holistic approach includes staying hydrated, eating a mineral-rich diet, and getting enough sleep

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It is not a cosmetic serum and is not intended for human or veterinary use