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The combined effects of GLP-1 in the gut and brain work together to help the body feel satiated with the amount of food consumed

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Further, in a comparison of levels of drug-metabolizing enzymes between transgenic or knockout mice and their parental strains using Western immunoblotting, increased expression of CYP2B and CYP3A isoforms was evident in XPA gene knockout mice with no differences from parental strains for rasH2, p53(+/-), and Tg.AC mice (Ariyoshi et al