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Since semaglutide can already slow down digestion, osmotic laxatives might be a good option to try with caution, as long as theyre used under medical guidance

MOTS-C and Retatrutide are not known to interact negatively with standard supplements including multivitamins, omega-3 fatty acids, creatine, protein powder, or common pre-workout ingredients

CrossRef Anti-Inflammatory Strategies Targeting Metaflammation in Type 2 Diabetes Alina Kuryowicz, Krzysztof Koniewski Molecules.2020

It means that even if a patch contains a clinically studied ingredient, that ingredient may not be reaching the bloodstream in any meaningful amount (7)