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Their fundamental hormonal alterations will make any minor dopamine or serotonin variations more noticeable. Overall, more research needs to be done on the area of interconnectedness between GLP-1, hormones, and sexual desire, said Hayley Miller, MD, obesity medicine specialist and metabolic health director at Nurx, an online womens health clinic
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Additionally, tirzepatide acts on central appetite regulation pathways, leading to reduced caloric intake and substantial weight losswith clinical trials showing approximately 15-20% weight reduction in obesity (SURMOUNT-1) and somewhat smaller reductions in diabetes trials
These typically improve over 24 weeks but can persist in some patients
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