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Serial assessments included clinical laboratory measures, efficacy measures, and biomarkers associated with neuroprotection and remyelination to assess the therapeutic potential of CNM-Au8 were accomplished ( 8 Potential toxicological risks and immunogenicity associated with nanoparticles Physicochemical properties of the NPs provide significant advantages in a wide range of fields, particularly in medicine and industry (189) owing to their compact size, huge surface area, and substantial surface reactivity (190)

James SJ, Melnyk S, Fuchs G, Reid T, Jernigan S, Pavliv O, Hubanks A, Gaylor DW

Habig WH, Pabst MJ, Jakoby WB

The brain tissue of PD patients is typically characterized by the death of dopaminergic, neuromelanin-containing neurons in the area of locus coeruleus and substantia nigra