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In addition to its anti-inflammatory properties, omega-3 fatty acid consumption is positively associated with the reduction of risk for many other chronic diseases such as heart disease, stroke, rheumatoid arthritis, and cancer

There are two 2HG enantiomers: D-2-hydroxyglutarate (D2HG) and L-2-hydroxyglutarate (L2HG), with the former predominantly generated from IDH1 mutants and PHGDH while L2HG is primarily generated from the promiscuous activity of LDHA and MDH1/2 under hypoxic or acidic conditions and converted back to 2OG by L2HGDH

While the FDA definitions of categories 2 and 3 dont state overtly that substances in those categories may not be compounded, they do state that FDA can take regulatory action against pharmacies using those substances

doi: 10.1007/s40262-015-0343-6 131 KnudsenLBNielsenPFHuusfeldtPOJohansenNLMadsenKPedersenFZet al