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25-39% The estimated proportion of weight lost on GLP-1 therapy that may come from lean mass rather than fat, based on body composition analyses from clinical trial data. The precise figure varies by patient, dose, and whether resistance exercise is incorporated

In a yearlong study, subjects given L-carnitine (2 grams per day) in addition to sibutramine lost approximately four more pounds over the course of a year, compared to those given only sibutramine

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