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Plant, Cell and Environ
Farhangi MA
Where liraglutide carries a C16 fatty-acid moiety and exhibits a ~13-hour half-life, semaglutide was engineered with a longer C18 di-acid chain attached through an extended -glutamate2OEG linker, a design change that extends serum half-life to approximately 7 days through significantly tighter albumin binding
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