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However, genetics provide context, not certainty
Moreover, the availability of multiple effective obesity pharmacotherapies with different mechanisms of action will provide clinicians the opportunity to select treatments based on patient preference, underlying comorbidities, medication safety profile and treatment response, with an aim to achieve the individualised WL targets, improve the overall health and/or the quality of life [7]
This has not been confirmed in humans but is listed as a contraindication as a precaution
GLP-1R are expressed by neurons, glia cells do not express this receptor but induced expression when activated in an inflammatory response (17, 25)
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