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Microglial activation, neutrophil infiltration, and the release of pro-inflammatory cytokines collectively exacerbate BBB breakdown and neuronal death
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2.3 C-3 hydroxyl group modification 2.3.1 Esterification The incorporation of nitrogen-containing heterocyclic moieties into C-3 hydroxyl group esterification modifications has been shown to substantially augment cytotoxic potency (Li X
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