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Cao J, Belousoff MJ, Liang YL, Johnson RM, Josephs TM, Fletcher MM, et al

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Magnesium is another key player

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Since ceruloplasmin binds 85-95% of circulating copper and facilitates its safe transport, reduced synthesis means a higher fraction of "free" (non-ceruloplasmin-bound) copper in circulation

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183 Aspirin further reduces breast cancer metastasis by sensitizing cancer cells to anoikis, thereby decreasing circulating tumor cells and lung metastasis through inhibition of the thromboxane A2 (TXA2) pathway

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