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IHC staining IHC staining was used to evaluate the level and distribution of proteins in tumor tissues

SAR441255 also reduced body weight (~12%) in DIO monkeys after 7 weeks, confirming its efficacy in mammalian species (66, 69)

There were also no significant differences between groups on frailty status score, physical function, nutritional status, and the biochemical tests using MannWhitney test