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Eur Urol (2018) 73(5):71523

For example, while Gln and the Gln-Glu cycle are believed to regulate Glu, an increased cycle turnover could mitigate excessive glutamatergic activity and maintain a balanced excitatory tone [15, 61]

BSO treatment was performed similarly as for ITCs by adding it (100 mM stock solution prepared in water) to the medium (either on its own or in combination with ITC) to obtain BSO concentrations ranging from 50 M to 700 M

Its primary function is in tissue repair: it promotes actin polymerization (required for cell movement), upregulates anti-inflammatory proteins, and stimulates the migration of keratinocytes and endothelial cells that are needed to close and repair damaged tissue