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The identification of comorbidities was based on ICD-10-CM codes
Metformin has been found to produce antidepressive effects by enhancing the responsiveness of the serotoninergic neurons in the dorsal raphe [47], but the main impact of GLP-1 is exerted by AMP-activated protein kinase (AMPK), a major cellular regulator of lipid and glucose metabolism [48]
Remember that individual responses can vary
Better rest improves mood, memory, and daytime performance
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