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Defective HR engendered by the PDS5B 17A mutation was also reflected in the sensitivity of mutant cells to the PARP inhibitor Rucaparib, though this sensitivity was not as severe as that observed with BRCA2 knockdown (Supplementary Fig
doi: 10.1016/j.eclinm.2021.100979 99 GorelikYGhersinILujanRShlonDLoewenberg WeisbandYBen-TovAet al
In research settings, PCO can be quantified using validated imaging methods such as POCOman (105) or AQUAII (106) to assess its severity and visual impact
Lamb and pork are also good sources of L-carnitine
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