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[12] [13] Diagnosis involves excluding other conditions that might explain the symptoms, with basic investigations such as full blood count, inflammatory markers (ESR/CRP), thyroid function, and vitamin D levels often considered

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35 Alternatively, reporting of neurochemical levels relative to a reference neurochemical in the same voxel is a common approach, as measurements are technologically uncomplicated (only a single spectrum must be collected) and no correction for partial-volume effects is required